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Kai-Uwe Eckardt Selected Research

Erythropoietin

9/2022Erythropoietic effects of vadadustat in patients with anemia associated with chronic kidney disease.
11/2021Global Phase 3 programme of vadadustat for treatment of anaemia of chronic kidney disease: rationale, study design and baseline characteristics of dialysis-dependent patients in the INNO2VATE trials.
1/2021Vadadustat in Patients with Anemia and Non-Dialysis-Dependent CKD.
1/2021Safety and Efficacy of Vadadustat for Anemia in Patients Undergoing Dialysis.
1/2021Cardiovascular safety and efficacy of vadadustat for the treatment of anemia in non-dialysis-dependent CKD: Design and baseline characteristics.
12/2019Now a Nobel gas: oxygen.
1/2017Change in Hemoglobin Trajectory and Darbepoetin Dose Approaching End-Stage Renal Disease: Data from the Trial to Reduce Cardiovascular Events with Aranesp Therapy Trial.
12/2010Inhibition of prolyl hydroxylases increases erythropoietin production in ESRD.
6/2010Enhanced progenitor cell recruitment and endothelial repair after selective endothelial injury of the mouse kidney.
2/2009Erythropoietin and microvascular diabetic complications.
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Kai-Uwe Eckardt Research Topics

Disease

79Chronic Renal Insufficiency
10/2022 - 06/2002
72Hypoxia (Hypoxemia)
09/2022 - 05/2002
27Anemia
09/2022 - 07/2002
21Renal Insufficiency (Renal Failure)
05/2022 - 06/2002
20Chronic Kidney Failure (Chronic Renal Failure)
03/2021 - 01/2002
19Inflammation (Inflammations)
01/2022 - 07/2003
19Kidney Diseases (Kidney Disease)
01/2022 - 06/2005
15Fibrosis (Cirrhosis)
05/2022 - 06/2002
15Hypertension (High Blood Pressure)
01/2022 - 12/2008
14Cardiovascular Diseases (Cardiovascular Disease)
10/2022 - 07/2009
14Acute Kidney Injury (Acute Renal Failure)
01/2021 - 12/2005
13Cysts
01/2020 - 01/2009
12Proteinuria
10/2022 - 06/2002
10Neoplasms (Cancer)
01/2022 - 05/2002
9COVID-19
01/2022 - 01/2020
9Myocardial Infarction
01/2022 - 05/2002
9Ischemia
11/2019 - 07/2002
9Type 2 Diabetes Mellitus (MODY)
01/2019 - 07/2009
9Iron Deficiencies
01/2018 - 07/2006
9Autosomal Dominant Polycystic Kidney (ADPKD)
03/2016 - 01/2009
8Diabetes Mellitus
05/2022 - 11/2016
8Infections
03/2022 - 08/2010
8Albuminuria
01/2022 - 06/2005
8Pure Red-Cell Aplasia
11/2009 - 09/2002
7Heart Failure
10/2022 - 01/2019
7Stroke (Strokes)
01/2022 - 11/2009
7Vascular Calcification
12/2021 - 01/2018
6Critical Illness (Critically Ill)
01/2022 - 01/2002
6Polycystic Kidney Diseases (Polycystic Kidney Disease)
01/2020 - 03/2007
5Gout
12/2021 - 04/2015
5Renal Cell Carcinoma (Grawitz Tumor)
10/2016 - 05/2002
4Disease Progression
08/2020 - 05/2002
4Hyperplasia
02/2013 - 05/2009
4Body Weight (Weight, Body)
01/2013 - 09/2003
3Coronary Artery Disease (Coronary Atherosclerosis)
10/2022 - 01/2020
3Shock
01/2022 - 11/2005
3Acidosis
09/2020 - 01/2006
3Kidney Neoplasms (Kidney Cancer)
10/2016 - 05/2002
3Polycythemia (Erythrocytosis)
04/2008 - 05/2002

Drug/Important Bio-Agent (IBA)

42Transcription Factors (Transcription Factor)IBA
01/2021 - 05/2002
32Oxygen (Dioxygen)IBA
01/2021 - 08/2002
28ErythropoietinFDA Link
09/2022 - 01/2002
23Proteins (Proteins, Gene)FDA Link
01/2022 - 06/2002
19CreatinineIBA
10/2022 - 06/2002
15AlbuminsIBA
10/2022 - 06/2005
15Biomarkers (Surrogate Marker)IBA
10/2022 - 01/2009
15HematinicsIBA
09/2022 - 02/2004
15Darbepoetin alfa (Aranesp)FDA Link
09/2022 - 07/2009
14Hemoglobins (Hemoglobin)IBA
09/2022 - 05/2002
12C-Reactive ProteinIBA
01/2022 - 05/2002
11Prolyl-Hydroxylase InhibitorsIBA
09/2022 - 06/2003
11IronIBA
09/2022 - 01/2002
11Prolyl Hydroxylases (Prolyl Hydroxylase)IBA
01/2019 - 06/2003
10CytokinesIBA
01/2022 - 01/2002
7Messenger RNA (mRNA)IBA
01/2022 - 05/2002
7OxalatesIBA
01/2021 - 01/2016
7Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2021 - 07/2002
7AntibodiesIBA
07/2020 - 09/2002
6vadadustatIBA
09/2022 - 01/2021
6UromodulinIBA
05/2022 - 09/2014
6Uric Acid (Urate)IBA
12/2021 - 04/2015
6CollagenIBA
01/2016 - 06/2006
5omega-Chloroacetophenone (Mace)IBA
10/2022 - 01/2020
5Glucose (Dextrose)FDA LinkGeneric
12/2021 - 12/2005
5Pharmaceutical PreparationsIBA
01/2021 - 08/2010
5ChloridesIBA
01/2020 - 03/2014
5ferric carboxymaltoseIBA
09/2017 - 04/2014
5SaltsIBA
03/2013 - 09/2003
4HDL CholesterolIBA
12/2021 - 01/2020
4Protein Isoforms (Isoforms)IBA
01/2020 - 02/2005
4LipidsIBA
11/2017 - 11/2010
4Epoetin Alfa (Epogen)FDA Link
10/2017 - 05/2004
4SodiumIBA
06/2017 - 01/2012
4Carbon MonoxideIBA
01/2017 - 07/2002
4CalciumIBA
12/2016 - 03/2014
4EnzymesIBA
11/2011 - 06/2002
3Troponin T (Troponin T1)IBA
10/2022 - 10/2011
3Antiviral Agents (Antivirals)IBA
01/2022 - 01/2019
3LDL CholesterolIBA
01/2022 - 01/2020
3Phosphates (Orthophosphate)IBA
12/2021 - 01/2018
3Cholecalciferol (Vitamin D3)FDA Link
12/2021 - 01/2018
3Lactic Acid (Lactate)FDA LinkGeneric
10/2021 - 11/2011
3AntigensIBA
01/2021 - 12/2014
3MineralsIBA
01/2020 - 11/2009
3Antihypertensive Agents (Antihypertensives)IBA
10/2019 - 02/2010
3ApoferritinsIBA
09/2017 - 01/2016
3TOR Serine-Threonine KinasesIBA
01/2017 - 01/2009
3Acetates (Acetic Acid Esters)FDA Link
01/2017 - 03/2012
3ReninIBA
10/2015 - 11/2009
3Brain Natriuretic Peptide (Natrecor)FDA Link
11/2011 - 11/2010
3Peptides (Polypeptides)IBA
11/2009 - 06/2002
3ElementsIBA
10/2009 - 07/2006
3Contrast MediaIBA
05/2009 - 05/2008

Therapy/Procedure

38Therapeutics
01/2022 - 01/2002
16Renal Replacement Therapy (Therapies, Renal Replacement)
01/2022 - 11/2006
11Transplantation
01/2022 - 06/2005
8Renal Dialysis (Hemodialysis)
01/2022 - 10/2010
6Kidney Transplantation
07/2021 - 01/2007
3Critical Care (Surgical Intensive Care)
01/2021 - 11/2006
3Catheters
05/2015 - 07/2013